{"id":22276,"date":"2025-10-09T12:13:38","date_gmt":"2025-10-09T12:13:38","guid":{"rendered":"https:\/\/itbusinesstoday.com\/?p=22276"},"modified":"2025-10-09T12:13:38","modified_gmt":"2025-10-09T12:13:38","slug":"alpha-fusion-and-kobe-hospital-launch-at-211-drug-system","status":"publish","type":"post","link":"https:\/\/itbusinesstoday.com\/ja\/health-tech\/pharma\/alpha-fusion-and-kobe-hospital-launch-at-211-drug-system\/","title":{"rendered":"\u30a2\u30eb\u30d5\u30a1\u30d5\u30e5\u30fc\u30b8\u30e7\u30f3\u3068\u795e\u6238\u75c5\u9662\u304cAt-211\u30c9\u30e9\u30c3\u30b0\u30b7\u30b9\u30c6\u30e0\u3092\u767a\u58f2"},"content":{"rendered":"<?xml encoding=\"utf-8\" ?><p>Alpha Fusion Inc. has announced a strategic collaboration with Kobe City Medical Center General Hospital (KCGH) to establish a domestic supply system for investigational drugs using Astatine-211 (At-211). This initiative represents a major milestone toward launching what is expected to be the world&rsquo;s first company-sponsored clinical trial utilizing At-211, a promising radionuclide for targeted alpha therapy.<\/p><p>Under the collaboration, KCGH has received approval from Japan&rsquo;s Nuclear Regulation Authority to use At-211 and has begun technology transfer and test manufacturing of Alpha Fusion&rsquo;s lead candidate, af-001, which targets differentiated thyroid cancer. The hospital&rsquo;s radioactive investigational drug GMP manufacturing facility, renowned for its expertise in handling short-lived radionuclides for PET imaging, will play a central role in producing At-211-based investigational drugs under clinical-grade conditions.<\/p><p>At-211\u306f\u3001\u534a\u6e1b\u671f\u304c\u77ed\u304f\uff08\u7d047.2\u6642\u9593\uff09\u3001\u5d29\u58ca\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u304c\u5358\u7d14\u3067\u3001\u6cbb\u7642\u7cbe\u5ea6\u304c\u9ad8\u3044\u305f\u3081\u3001\u6a19\u7684\u30a2\u30eb\u30d5\u30a1\u7dda\u6cbb\u7642\u306e\u305f\u3081\u306e\u6700\u3082\u6709\u671b\u306a\u653e\u5c04\u6027\u6838\u7a2e\u306e1\u3064\u3068\u307f\u306a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u307e\u3067\u306f\u3001\u5b89\u5b9a\u3057\u305f\u4f9b\u7d66\u30b7\u30b9\u30c6\u30e0\u304c\u306a\u304b\u3063\u305f\u305f\u3081\u3001At-211\u306e\u81e8\u5e8a\u7814\u7a76\u306f\u3059\u3079\u3066\u5b66\u8853\u7684\u306a\u74b0\u5883\u306b\u9650\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u696d\u754c\u4e3b\u5c0e\u306eAt-211\u4f9b\u7d66\u30c1\u30a7\u30fc\u30f3\u3092\u78ba\u7acb\u3059\u308b\u3053\u3068\u3067\u3001\u30a2\u30eb\u30d5\u30a1\u30fb\u30d5\u30e5\u30fc\u30b8\u30e7\u30f3\u3068KCGH\u306f\u3001\u30a2\u30eb\u30d5\u30a1\u653e\u5c04\u6027\u533b\u85ac\u54c1\u306e\u5546\u696d\u5316\u3068\u81e8\u5e8a\u5fdc\u7528\u306e\u65b0\u305f\u306a\u6bb5\u968e\u3092\u958b\u62d3\u3057\u307e\u3059\u3002<\/p><h4>\u3053\u3061\u3089\u3082\u304a\u8aad\u307f\u304f\u3060\u3055\u3044\uff1a <a class=\"p-url\" href=\"https:\/\/itbusinesstoday.com\/ja\/health-tech\/pharma\/rentschler-biopharma-expands-in-japan-and-korea\/\" rel=\"bookmark\">\u30ec\u30f3\u30c8\u30b7\u30e5\u30e9\u30fc\u30d0\u30a4\u30aa\u30d5\u30a1\u30fc\u30de\u304c\u65e5\u672c\u3068\u97d3\u56fd\u3067\u4e8b\u696d\u3092\u62e1\u5927<\/a><\/h4><p>\u3053\u306e\u30b3\u30e9\u30dc\u30ec\u30fc\u30b7\u30e7\u30f3\u306f <a href=\"https:\/\/chuo.kcho.jp\/\" data-no-translation=\"\">Kobe City Medical Center General Hospital (KCGH)<\/a>&rsquo;s GMP production with Alpha Fusion&rsquo;s nationwide network of cyclotron facilities capable of producing At-211, creating the world&rsquo;s first multi-site At-211 supply chain that connects radionuclide production, investigational drug manufacturing, and clinical trial execution.<\/p><p>Linking a major payments brand to a crypto platform requires compliance, security, and teamwork with regulators. Asian governments, like Japan, South Korea, and Singapore, are taking strong action against crypto exchanges and stablecoins. These alliances will lead regulators to rethink their approach to payment platforms that combine fiat and digital assets. Alpha Fusion&rsquo;s top candidate, af-001, leverages the special traits of At-211. Af-001 targets thyroid cancer cells using the Sodium-Iodide Symporter (NIS). It works like iodine. It focuses specifically on these cells. This low-radiation therapy allows patients to receive treatment without an overnight stay. This is a safer, more convenient choice for people with differentiated thyroid cancer.<\/p><p>\u3053\u306e\u753b\u671f\u7684\u306a\u9032\u6b69\u306b\u3088\u308a <a href=\"https:\/\/alpha-fusion.com\/\" data-no-translation=\"\">Alpha Fusion<\/a> \u306f\u3001\u81e8\u5e8a\u6bb5\u968e\u306eAt-211\u5275\u85ac\u306e\u4e16\u754c\u7684\u30ea\u30fc\u30c0\u30fc\u3067\u3059\u3002\u307e\u305f\u3001\u6a19\u7684\u03b1\u7642\u6cd5\u3092\u7532\u72b6\u817a\u304c\u3093\u304b\u3089\u4ed6\u306e\u56fa\u5f62\u304c\u3093\u306b\u62e1\u5927\u3059\u308b\u305f\u3081\u306e\u57fa\u76e4\u3092\u7bc9\u304d\u307e\u3059\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>Alpha Fusion Inc. has announced a strategic collaboration with Kobe City Medical Center General Hospital (KCGH) to establish a domestic supply system for investigational drugs using Astatine-211 (At-211). This initiative represents a major milestone toward launching what is expected to be the world&rsquo;s first company-sponsored clinical trial utilizing At-211, a promising radionuclide for targeted alpha therapy.Under the collaboration, KCGH has received approval from Japan&rsquo;s Nuclear Regulation Authority to use At-211 and has begun technology transfer and test manufacturing of Alpha Fusion&rsquo;s lead candidate, af-001, which targets differentiated thyroid cancer. The hospital&rsquo;s radioactive investigational drug GMP manufacturing facility, renowned for its expertise in handling short-lived radionuclides for PET imaging, will play [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":22277,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"wprm-recipe-roundup-name":"","wprm-recipe-roundup-description":"","postBodyCss":"","postBodyMargin":[],"postBodyPadding":[],"postBodyBackground":{"backgroundType":"classic","gradient":""},"footnotes":""},"categories":[208,89,211,237,182,206],"tags":[5815,8393,8392,424,8394],"ppma_author":[572],"class_list":["post-22276","post","type-post","status-publish","format-standard","has-post-thumbnail","category-apac","category-health-tech","category-japan","category-news","category-pharma","category-regional","tag-alpha-fusion","tag-drug-supply-system","tag-kcgh","tag-pharma","tag-test-manufacturing"],"yoast_head":"<!-- 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